TGYBIO supply factory price CAS196618-13-0 antiviral oseltamivir powder
Name: Oseltamivir
CAS No.: 196618-13-0
Molecular formula: C16H28N2O4
Molecular weight: 312.4
Appearance: Off-White to Pale Beige powder
Oseltamivir Phosphate is an anti-influenza virus drug under the trade name Tamiflu. Its appearance is white to yellow-white powder. It can be divided into type A (type A) and type B (type B) influenza viruses. Selective inhibitors of the enzyme, by inhibiting the neuraminidase of the virus, prevent the virus from being released and spread from the infected cells, thereby achieving the goal of controlling the symptoms of the flu. Clinically used for the prevention of influenza A and B in adults and children aged 1 and over, and prevention of influenza A and B in adults and teenagers 13 years and older. Oseltamivir phosphate rapidly metabolizes to oseltamivir carboxylate after absorption from the gastrointestinal tract, and at least 75% of the oral dose is involved in systemic circulation in the form of oseltamivir carboxylate. Is a potent and unique neuraminidase inhibitor that acts on all aspects of influenza virus infection and prevents the replication of all clinically relevant influenza virus strains A or B.
Application
Oseltamivir phosphate is used for the prevention and treatment of influenza caused by influenza A and B viruses.It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system.Oseltamivir's risk-benefit ratio is controversial.
Oseltamivide phosphate is an anti-influenza virus drug, trade name Tamiflu,white to yellow-white powder appearance can be divided into A (A) and B (B) influenza virus nerve Acidase-selective inhibitors,by inhibiting the virus neuraminidase to stop the virus from being infected cells and disseminated, so as to achieve the purpose of controlling flu symptoms.
Clinically for the prevention of influenza A and B influenza in adults and children aged 1 and over,adults and adults 13 and over 13 years of age.
Oseltamivide phosphate is rapidly metabolized to oseltamivir carboxylate by absorption through the gastrointestinal tract and at least 75 % of the oral dose is involved in systemic circulation in the form of oseltamivircarboxylate The active ingredient Is a potent and unique neuraminidase inhibitor that acts on all aspects of influenza virus infection and prevents the replication of all clinically relevant strains of influenza A or B viruses. In vitro in very low nanomolarconcentrations that have inhibitory effect. The active metabolite was observed to inhibit the growth of influenza virus in vitro and it was also observed in vivo to inhibit the replication and pathogenicity of influenza virus. Oseltamivide phosphate reduces the spread of influenza A or B viruses by inhibiting the release of the virus from the infected cells.
It has been studied for its potential use in the treatment of jaundice, dysentery, hypertension, inflammation, and liver-related diseases. This compound also has weak in vitro activity against flavivirus.