| Powder: | Yes |
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| Customized: | Customized |
| Certification: | GMP, ISO 9001, USP, BP |
| Suitable for: | Elderly, Adult |
| State: | Powder |
| Purity: | >98% |
| Samples: |
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| Customization: |
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Tetracaine hydrochloride (TCH) is one of the potent local anesthetics. A kinetic study of oxidation of tetracaine hydrochloride by sodium N-chlorobenzenesulfonamide (chloramine-B or CAB) has been carried in HClO4 medium at 303 K. The rate shows first-order dependence on, shows fractional-order dependence on, and is self-governing on acid concentration. Decrease of the dielectric constant of the medium, by adding increased the rate. Variation of ionic strength and addition of benzenesulfonamide or NaCl has no significant effect on the rate.
The reaction was studied at different temperatures and the activation parameters have been evaluated. The
stoichiometry of the reaction was found to be 1: 5 and the oxidation products were identified by spectral analysis. The conjugate-free acid C6H5SO2NHCl of CAB is postulated as the reactive oxidizing species. The observed results have been explained by plausible mechanisms and the related rate law has been deduced.
Works of Tetracaine HCl Powder
(1) In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors)
that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function.
At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high
concentrations, tetracaine blocks release completely.
(2) Tetracaine is the T in Tac, a mixture of 5 to 12 per cent tetracaine, 5M(per myriad), a half per mille (0.5‰),
or .05 percent (1 part in 2000), and 4 or 10 percent hydrochloride used in ear, nose & throat surgery and
in the emergency department where numbing of the surface is needed rapidly, especially when children have
been injured in the eye, ear, or other sensitive locations.
(3) Tetracaine is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed
esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic
acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium etho.
1) Tetracaine is a local anesthetic (numbing medicine). It works by blocking nerve signals in your body.
2) Tetracaine topical may also be used for purposes not listed in this medication guide.
3) Tetracaine topical (for the skin) is used to numb different parts of the body before a medical test or procedure.
4) In the manufacture of a pharmaceutical preparation for external use, to relieve the pain of drugs or medication lesions pain.
Side Effect of Tetracaine HCl Powder
Common side effects include a brief period of burning at the site of use. Allergic reactions may uncommonly
occur. Long-term use is generally not recommended as it may slow the healing of the eye. It is unclear if use during
pregnancy is safe for the baby. Tetracaine is in the ester-type local anesthetic family of medications. It works by
blocking the sending of nerve impulses.
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