| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
|
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Product Name
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Bromopyruvic acid |
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Specification
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99%
|
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Molecular Formula
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C3H3BrO3 |
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Molecular Weight
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166.96
|
3-Bromopyruvate enhances TRAIL-induced apoptosis in breast cancer cells
3-Bromopyruvate (Bromopyruvic acid), a hexokinase II inhibitor, can induce apoptosis in hepatocellular carcinoma cells by inducing endoplasmic reticulum (ER) stress
3-Bromopyruvate inhibits ATP generation and upregulates the expression of DR5. 3-Bromopyruvate upregulates CHOP, GRP78 and the phosphorylation of augments TRAIL-induced Bax and caspase-3 levels
3-Bromopyruvate (Bromopyruvic acid) is an analogue of pyruvate and a potent hexokinase (HK)-II inhibitor with high tumor selectivity. 3-Bromopyruvate inhibits cell growth and induces apoptosis through interfering with glycolysis. 3-Bromopyruvate induces autophagy by stimulating ROS formation in breast cancer cells. Antimicrobial activities
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