| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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Product Name: Miltefosine
Structural formula: C21H46NO4P
Molecular weight: 407.57
CAS NO.: 58066-85-6
Appearance: White to off-white powder
Miltefosine is a phospholipid drug. Chemically it is a derivative of alkylphosphocholine compounds discovered in the early 1980s. It was developed in the late 1980s as an anticancer drug. Simultaneously but independently it was found that the drug could kill Leishmania parasites, and since the mid-1990s successful clinical trials were conducted. The drug became the first (and still the only prescribed) oral drug in the treatment of leishmaniasis.
It is now known to be a broad-spectrum antimicrobial drug, active against pathogenic bacteria and fungi, as well as humantrematode Schistosoma mansoni.
Miltefosine is usedfor the treatment of visceral and cutaneous leishmaniasis, and is undergoing clinical trialsfor this use in several other countries, such as Brazil and Guatemala. Several medical agents have some efficacy against visceral or cutaneous leishmaniasis, however a 2005 survey concluded that miltefosine is the only effective oral treatment for both forms of leishmaniasis.
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