| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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Synonyms: TRETINOIN VITAMIN A ACID;TRANS-RETINOIC ACID;TRANS VITAMIN A ACID;VITAMIN A ACID;RETINOIC ACID
CAS: 302-79-4
MF: C20H28O2
MW: 300.44
EINECS: 206-129-0
mp: 180-181 °C(lit.)
storage temp: 2-8°C
Water Solubility: insoluble
Appearance: yellow powder
Retinoic Acid Powder is yellow crystalline powder. Retinoic Acid Powder easily dissolved in chloro and dissolved in carbinol, ethanol and retinoic acid also dissolved in vegetable oil and lipid. Retinoic Acid Powder instability exposed in light and caloricr, easily absorbing moisture and metamorphosed in water. Tretinoin is the acid form of vitamin A and is also known as all-trans retinoic acid or ATRA. It is a drug commonly used to treat acne vulgaris and keratosis pilaris. It is available as a cream or gel It is also used to treat acute promyelocytic leukemia. It is also available as a generic.
Medical uses:
Skin use
Tretinoin is most commonly used to treat acne. It is also used off-label to treat and reduce the appearance of stretch marks by increasing collagen production in the dermis.
In topical form, this drug is pregnancy category C and should not be used by pregnant women.
People using the topical form should not also use any cream or lotion that has a strong drying effect, contains alcohol, astringents, spices, lime, sulfur, , or aspirin, as these may interact with tretinoin or exacerbate its side effects.
Leukemia
Tretinoin is used to induce remission in people with acute promyelocytic leukemia who have a mutation (the t(15;17) translocation 160 and/or the presence of the PML/RARα gene) and who don't respond toanthracyclines or can't take that class of drug. It is not used for maintenance therapy.
In oral form, this drug is pregnancy category D and should not be used by pregnant women as it may harm the fetus.
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