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Nifedipine is also called the nifedipine, the flat, benzene, nitrate is a kind of two hydrogen class calcium antagonists, inhibit myocardial and vascular smooth muscle of Ca2 + uptake, expansion of coronary artery, increase coronary blood flow, improve myocardial ischemia tolerance, expands around the small artery at the same time, reduce the peripheral vascular resistance, alleviate coronary artery spasm, increase the coronary flow, improve myocardial ischemia, making the blood pressure to drop. Low dose dilation of coronary artery does not affect blood pressure. For the prevention and treatment of coronary heart disease angina, no adverse effects on respiratory function, especially for coronary artery spasm caused by angina and suffering from respiratory obstructive disease angina, the best effect, the effect is better than receptor blockers. It is also suitable for all types of hypertension, including severe and refractory hypertension. For the treatment of refractory congestive heart failure, this product can be taken for a long time. It is also used for the treatment of primary pulmonary hypertension, diffuse esophageal spasm and bronchial asthma, duodenal bulbous ulcer, urethral obstruction, sports asthma, achalasia of cardia and so on.
Nifedipine has a certain selectivity to vascular smooth muscle and a weak direct negative myodynamic effect and denaturation effect on the heart. Therefore, systemic administration of nifedipine does not cause slow heart rate, but shows an increase in heart rate reflex.
Long-acting coronary dilators. This product can increase coronary blood flow and reduce myocardial oxygen consumption. For acute and chronic coronary insufficiency, especially angina and myocardial infarction.