| Powder: | Yes |
|---|---|
| Customized: | Customized |
| Certification: | GMP, ISO 9001, USP, BP |
| Suitable for: | Elderly, Adult |
| State: | Powder |
| Purity: | >98% |
| Samples: |
|---|
| Customization: |
|---|
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Product Name |
RU-58841 |
Alias |
RU 58841, RU58841 |
CAS |
154992-24-2 |
MF |
C17H18F3N3O3 |
MW |
369.341 |
Purity |
98% |
Grade |
Pharmaceutical Grade |
Appearance |
white crystalline powder |
RU58841 is an androgen receptor blocker. It binds to androgen receptors with great specificity and tenacity,
but does not activate the receptor. Its presence on the receptor prevents androgens such as DHT from binding
to and activating the receptor. It has been extensively studied as a topical agent to treat acne and androgenetic
alopecia (1, 2, 3).
Androgenetic alopecia, or male-pattern balding, is caused by DHT binding to androgen receptors in the hair
follicles. Over time, in susceptible individuals, the activation of the androgen receptors causes the hair follicles
to stop producing normal hair and to undergo a process called miniaturization. In laboratory studies, RU58841
has been shown to be quite effective in competing against DHT for access to the androgen receptors.
Work of Ru58841 Powder
RU58841 works by binding to the androgen receptor in the hair follicle. Therefore androgens don't have the
chance to bind and start the chain reaction of androgenetic alopecia and begin the so called miniaturization
process. It has been demonstrated to interrupt this hair loss message locally so that normal hair growth could
continue.
RU 58841 is a specific androgen receptor antagonist or anti-androgen used as a topical treatment for acne,
androgenetic alopecia, and hirsutism. RU 58841 displays a high affinity for the hamster prostate and flank organ
(F.O.) androgen receptors. In vivo, when topically applied, it exerts a potent dose-dependent regression of F.O.
the area at a dose as low as 1 microgram/animal while being devoid of antiandrogenic activity on deep accessory
sex organs and of any effect on level up to 100 micrograms/animal. RU 58841 has a dramatic effect
on hair regrowth.
RU58841 is an androgen receptor blocker. It binds to androgen receptors with great specificity and tenacity
but does not activate the receptor. Its presence on the receptor prevents androgens such as DHT from binding
to and activating the receptor. It has been extensively studied as a topical agent to treat acne and androgenetic
alopecia (1, 2, 3).
Androgenetic alopecia, or male-pattern balding, is caused by DHT binding to androgen receptors in the hair follicles.
Over time, in susceptible individuals, the activation of the androgen receptors causes the hair follicles to stop
producing normal hair and undergo a process called miniaturization. In laboratory studies, RU58841 has been
shown to be quite effective in competing against DHT for access to the androgen receptors.
Suppliers with verified business licenses
Audited Supplier 
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