Factory Supply API 99% Baclofen CAS 1134-47-0 with Top Quality

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Solid
• Purity: >99%
• Model NO.: TGYBIO
• Product Name: 1134-47-0
• Appearance: White Powder
• Test Methods: HPLC
• Shelf Life: 2 Years
• Shipping Methods: DHL, FedEx, TNT and EMS
• MOQ: 1g
• Storage: 2 Years
• Spe: 99%
• Transport Package: Foil Bag, Box, Drum
• Specification: 99%
• Trademark: TGY
• Origin: China
• HS Code: 3001200010
• Production Capacity: 1500kg/Month

Product Description

 

product Name:	baclofen
CAS:	1134-47-0
MF:	C10H12ClNO2
MW:	213.66
EINECS:

Baclofen is a gamma-amino-butyric acid (GABA) derivative used as a skeletal muscle relaxant.Target: GABA ReceptorBaclofen, a lipophilic analog of gamma-aminobutyric acid, is clinically used to control spasticity. Baclofen pretreatment (3 mg/kg) not only prolonged the time taken for animals to reach a core body temperature of 40 degrees C (P < 0.001), but also reduced the percentage of rats attaining a core body temperature of 40 degrees C . Baclofen overdose may result in coma, apnea, autonomic disturbances, cardiac conduction abnormalities, and seizures. Levels obtained shortly after overdose correlate with length of mechanical ventilation 
_{It take antispasmodic effect by stimulating receptors to inhibit the release of excitatory amino acids such as glutamic acid, aspartic acid and thereby inhibiting the transfer of single and multi-synaptic reflex in central nervous system, brain and spinal cord}