Customization: | Available |
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Powder: | Yes |
Customized: | Customized |
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Product Name | Misoprostol/Misoprostil |
CAS No. | 59122-46-2 |
Molecular Formula | C22H38O5 |
Molecular Weight | 382.54 |
Appearance | White Powder |
Assay | 99% |
Grade | Pharmaceutical Grade |
Misoprostol is a synthetic steroid with antiprogestational effects indicated for the medical termination of intrauterine pregnancy through 49 days' pregnancy. Doses of 1 mg/kg or greater of have been shown to antagonize the endometrial and myometrial effects of progesterone in women. During pregnancy, the compound sensitizes the myometrium to the contraction-inducing activity of prostaglandins. also exhibits antiglucocorticoid and weak antiandrogenic activity. The activity of the glucocorticoid in rats was inhibited following doses of 10 to 25 mg/kg of . Doses of 4.5 mg/kg or greater in human beings resulted in a compensatory elevation of adrenocorticotropic hormone () and cortisol
The first chemically synthesized prostaglandin E1 anti-ulcer drug, which has a strong inhibitory effect on gastric acid secretion and prevents ulcer formation. The gastric acid that can be inhibited includes basal gastric acid secretion and stimulation caused by histamine pentagastrin, food or coffee. It also reduces gastric acid secretion at night. It is the earliest anti-peptic ulcer drug used in clinical practice. It is better than the receptor antagonists for prolonging the recurrence of ulcers, but the effect of alleviating the pain of peptic ulcers is not as good as that of the island receptor antagonists. For gastric and duodenal ulcers, especially in cases with low prostaglandin levels.
For gastric and duodenal ulcers, hemorrhagic gastritis, acute gastric mucosal lesions and other diseases.