| Powder: | Yes |
|---|---|
| Customized: | Non-Customized |
| Certification: | GMP, HSE, ISO 9001, USP, BP |
| Suitable for: | Adult |
| State: | Solid |
| Purity: | >98% |
| Samples: |
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| Customization: |
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| Common Name | Lamivudine | ||
|---|---|---|---|
| CAS Number | 134678-17-4 | Molecular Weight | 229.256 |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 475.4±55.0 °C at 760 mmHg |
| Molecular Formula | C8H11N3O3S | Melting Point | 177 ° |
Lamivudine is a potent nucleoside analog reverse transcriptase inhibitor (nRTI).It is marketed by GlaxoSmithKline with the brand names Zeffix, Heptovir, Epivir and Epivir-HBV. Lamivudine has been used for treatment of chronic hepatitis B at a lower dose than for treatment of HIV. It improves the seroconversion of e-antigen positive hepatitis B and also improves histology staging of the liver. Long term use of lamivudine unfortunately leads to emergence of a resistant hepatitis B virus (YMDD) mutant. Despite this, lamivudine is still used widely as it is well tolerated.
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