| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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| Index | Standard | Test Result |
| Characters | A White or yellowish white crystalline, | Conform |
| powder or crystals,very soluble in water, | ||
| very slightly souble in ethanol, | ||
| slightly soluble in glacial acetic acid. | ||
| Identification | A.B conform to standard | Conform |
| Loss on drying | Not more than 0.5% | 0.15% |
| Residue on ignition | Not more than 0.1% | Conform |
| Related substances | The sum of total impurities is not more than 1.0%. | Conform |
| any impurity is not more than 0.3% | ||
| Heavy metals | Not more than 0.001% | Conform |
| Assay | Calcuated on the dried basis, | 99.60% |
| C8H15N7O2S3 containsform 98.5% to 101.0% |
Famotidine, sold under the trade name Pepcid among others is a histamine H2 receptor antagonist that inhibitsstomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease.
(1)Relief of heartburn, acid indigestion, and sour stomach
(2)Treatment for gastric and duodenal ulcers
(3)Treatment for pathologic gastrointestinal hypersecretory conditions such as Zollinger-Ellison syndrome andmultiple endocrine adenomas
(4)Treatment for gastroesophageal reflux disease (GERD)
(5)Treatment for esophagitis
(6)Part of a multidrug regimen for Helicobacter pylori eradication, although omeprazole may be somewhat more effective.
(7)Prevention of NSAID-induced peptic ulcers.
Given to surgery patients before operations to reduce the risk of aspiration pneumonitis.Famotidine is also given to dogs and cats with acid reflux. Famotidine has been used in combination with an H1 antagonist to treat and prevent urticaria caused by an acute allergic reaction.
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