| CAS No.: | 70288-86-7 |
|---|---|
| Formula: | C48h74o14 |
| EINECS: | 274-536-0 |
| Appearance: | Powder |
| Source: | Organic Synthesis |
| Toxicity of High and Low: | Low Toxicity of Reagents |
| Samples: |
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| Customization: |
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Comman name |
Ivermetctin 99% |
|
Chemical name |
22,23-dihydro Avermectin B1 |
|
Appearance |
White or yellowish-white crystalline powder |
|
CAS No. |
70288-86-7 |
|
Function |
Antibacterial Drugs |
|
Solubility |
Easily soluble in organic solvent its solubility in water is very low |
|
Storage |
Sealed tightly and stored away from light in a cool and dry place. |
Ivermectin is widely used in cattle, sheep, horses, pigs, gastrointestinal nematodes, lung nematodes and parasitic arthropod, canine intestinal nematodes, ear mites, scabies mites, silk worm and microfilariae, gastrointestinal nematodes and external parasites and poultry. This product belong to the broad-spectrum drug resistant parasites.
Ivermectin for a variety of most of the life cycle of nematodes (but not all nematodes) role; For dish tail filarial microfilariae effectively, but for adult worms; For only in intestinal fecal round worms are also effective.
Ivermectin has the selective inhibitory effect, with no spinal nerve cells and muscle cells in the animal glutamic acid ion channels of the valve is the high binding affinity, leading to the proliferation of the chloride ion permeability of cell membrane, cause nerve cells or muscle cells hyperpolarization, parasites paralysis or death.
| TEST ITEMS | STANDARD PRESCRIBE | RESULTS |
Appearance |
White or yellowish-white crystalline powder | White crystalline powder |
Solubility |
Practically insoluble in water soluble in alcohol | Confroms |
| Identification | A:IR | Conforms |
| B:HPLC | ||
| Appearance of solution | Solution is clear ,≤BY7 | Clear, |
| Specific optical rotation | -17 to -20 ° | -18.5° |
| Related substances | ||
| Impurity with a relative retention of 1.3 to 1.5 (%) | ≤2.5 % | 1.60% |
| Any other impurity(%) | ≤ 1 | 0.50% |
| Total (%) | ≤5 | 3.30% |
| Ethanol (%) | ≤5.0 | 3.50% |
| Formamide (%) | ≤3.0% | 2.50% |
| Heavy metals (%) | ≤0.002 | <0.002% |
| Water (%) | ≤1.0 | 0.20% |
| Sulphated ash (%) | ≤0.1 | 0.05% |
| Content | ||
| H2B1(%) | 95.0-102.0 | 96.00% |
| H2B1a/H2B1(%) | ≥90.0 | 98.00% |
| Conclusion | This product complies with EP6.0 standard | |
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