Customization: | Available |
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Powder: | Yes |
Customized: | Customized |
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Hot selling high purity trilostane powder CAS13647-35-3
Product Name | Trilostane |
CAS No | 13647-35-3 |
EINECS No | 237-133-0 |
Color | White Powder |
Purity | 99% |
Certificate | KOSHER,Halal,ISO9001;SGS |
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Trilostane is an inhibitor of isoforms 3β-HSD and 3β-HSD2 of the enzyme 3β-hydroxysteroid dehydrogenase, which plays a role in adrenal steroid biosynthesis. Investigators believe that Arg195 in 3∫-HSD versus Pro195 in 3β-HSD2 attributes to the competitive inhibition of 3β-HSD, but not 3β-HSD2 by Trilostane. Research shows that trilostane is effective in suppressing the intracellular production of dihydro in LNCaP-FGC prostate cancer cells and inhibiting cortisol biosynthesis in the human adrenal gland. This product serves as a useful tool in steroid biosynthesis research.