Customization: | Available |
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Powder: | Yes |
Customized: | Customized |
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Item Name | Miconazole |
CAS NO | 22916-47-8 |
Molecular Formula | C18H14Cl4N2O |
Molecular weight | 416.13 |
Apparence | White Powder |
Package | Aluminum Bag;Drums;Paper Box Outside |
Function |
Miconazole is an antifungal synthetic derivative of imidazole and used in the treatment of candidal skin infections, Miconazole selectively affects the integrity of fungal cell membranes, high in ergosterol content and different in composition from mammalian cells membranes. Miconazole is used to treat ring worm, pityriasis versicolor, and yeast infections of the skin or vagina. It is applied to the skin or vagina as a cream or ointment. |
Miconazole nitrate is a kind of antifungal agent which is the drug "Dakelin" which we are familiar with as commonly used drugs for treating skin ringworm. It has various kinds of effects. It inhibit the biosynthesis of ergosterol which is the fungal cell membrane component, causing damage to the cell membrane structure, increasing the membrane permeability, resulting in the leakage of the intracellular components and inhibiting the glucose utilization, preventing the nutrient uptake, and finally leading to fungal cell death. It is therefore suitable for the treatment of tinea, jock itch, ringworm, athlete's foot, tinea versicolor and paronychomycosis as well as the vaginal infection and secondary infection caused by the yeast (such as Candida) and Gram-positive bacteria. It is also effective in treating otitis externa and bacterial skin infections.