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Product name: 5a-hydroxy laxogenin, 5 Alpha-Hydroxy-Laxogenin Molecular Formula: C27H42O5 Molecular Weight: 446.619 Cas No: 56786-63-1 Appearance: White Fine Powder Capacity: 10kgs per month Source: synthetic Purity (HPLC) >99.0% Place of Origin: China TGY-Lab Packing: As per client's requirements Minimum Order Quantity: 100g Storage: Store in cool & dry place, Keep away from strong light and heat for 2 years |
Laxogenin (3beta-hydroxy-25D,5alpha-spirostan-6-one) is a compound sold in various forms as a muscle-toning supplement. It belongs to a class of plant hormones called brassinosteroids, which have a similar structure to animal steroid hormones. In plants, they work to boost growth.
The underground stems of the Asian plant Smilax sieboldii contain approximately 0.06% laxogenin and are its main natural source. Laxogenin is also obtained from Chinese onion (Allium chinense) bulbs.
Laxogenin in supplements is produced from the more common plant steroid, diosgenin. In fact, diosgenin is used as a raw material for over 50% of synthetic steroids including progesterone, corti.sone.
5a-Hydroxy LaxogeninBenefits:
Laxogenin is sold as a muscle toning supplement for athletes and bodybuilders. It's claimed to increase protein production in muscles by 200%.
In an old Russian study in rats, brassinosteroid derivatives with a similar structure to laxogenin increased total weight and protein content of the liver, heart, kidneys, and leg muscles without raising the levels of sex hormones or mimicking their effects.
Similarly, another plant brassinosteroid increased food intake, weight gain, lean body weight, the weight of leg muscles, and physical fitness in rats. In muscle cells, both this molecule and its synthetic derivatives promoted protein production and reduced protein breakdown.
A class of plant chemicals with a similar structure to brassinosteroids (phytoecdysteroids) increased muscle in animals and protein production in muscle cells.
While all these substances are similar, they are not identical. It is possible that laxogenin (and its derivatives in supplements) have similar anabolic effects. But since these have not been studied yet, we are still in the dark when it comes to the muscle-building potential of laxogenin.
No clinical evidence supports the use of laxogenin for any of the conditions listed in this section. Below is a summary of the existing animal and cellbased research, which should guide further investigational efforts. However, the studies listed below should not be interpreted as supportive of any health benefit.