| Product name |
Best Price CAS 204255-11-8 Oseltamivir Phosphate Powder |
| Appearance |
white powder |
| Cas |
204255-11-8 |
| Assay |
99% |
| Shelf Life |
24 months when properly stored |
| Storage |
Keep in a cool, dry, dark location |
What is Oseltamivir phosphate ?
Oseltamivir is an drug,a neuramini-dase inhibi-tor used in the treatment and prophylaxis of both influenza A and influenza B.
Oseltamivir is a prodrug (usually administered as phosphate),Oseltamivir phosphate is hydrolysed hepatically to the active metabolite, the free carboxylate of oseltamivir (GS4071).
Like zanamivir,oseltamivir acts as a transition-state analogue inhibitor of influenza neuraminidase.
Oseltamivir phosphate is an ethyl ester prodrug requiring ester hydrolysis for conversion to the active form, oseltamivir
carboxylate. The proposed mechanism of action of oseltamivir is inhibition of influenza virus neuraminidase with the possibility of alteration of virus particle aggregation and release.
Oseltamivide is an anti-influenza virus drug, trade name Tamiflu,white to yellow-white powder appearance can be divided into A (A) and B (B) influenza virus nerve Acidase-selective inhibitors, by inhibiting the virus neuraminidase to stop the virus from being infected cells and disseminated, so as to achieve the purpose of controlling flu ymptoms Clinically for the prevention of influenza A and B influenza in adults and children aged 1 and over,adults and adults 13 and over 13 years of age.Oseltamivide is rapidly metabolized to oseltamivir carboxylate by absorption through the gastrointestinal tract and at least 75% of the oral dose is involved in systemic circulation in the form of oseltamivir carboxylate.
The active ingredient Is a potent and unique neuraminidase inhibitor that acts on all aspects of influenza virus infection and prevents the replication of all clinically relevant strains of influenza A or B viruses.
In vitro in very low nanomolar concentrations that have inhibitory effect. The active metabolite was observed to inhibit the
growth of influenza virus in vitro and it was also observed in vivo to inhibit the replication and pathogenicity of influenza
virus.
Oseltamivide reduces the spread of influenza A or B viruses by inhibiting the release of the virus from the infected cells.
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