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N-Methyl-D-aspartic acid or N-Methyl-D-aspartate (NMDA) is an amino acid derivative that acts as a specific agonist at the NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor. Unlike glutamate, NMDA only binds to and regulates the NMDA receptor and has no effect on other glutamate receptors.
1. NMDA can participate in hypothalmo-neurohypophysial system neuroendocrine regulatiion. NMDA with suitable concentration can obviously improve secretion of hypothalamus nerve cell SS and expression of mRNA, improve Ca2+ level in cell and lower cAMP concentration.
2. NMDA plays an important roleintheneuroendocrine regulation. NMDA with suitable concentrationcan affect the organismendocrine system, especially promote the hormone significantly (GH) secretion of animal organism toincrease blood GH level.
3. NMDA can affect cell proliferation activity by inhibiting DNA synthesis of PC12 cells. So it can be used for the synthesis of anticancer drugs.
4. NMDA with suitable concentrationcan significantly promote releasing g hormone in animal adenohypophysis, yellow pituitary erythropoetin, gonadotropn and secretionofprolactin. It can be used as a new feed additives with efficient growth promotion.
5. NMDA can be used as a new functional food additives.Nutritional supplement, nutrition enhancer, dietary supplements, heatlh food additives, pharmaceutical raw material. sport supplements, sport nutrtional supplements.