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Finasteride is an antiandrogen that acts by inhibiting type II 5-alpha reductase. It is used as a treatment in benign prostatic hyperplasia (BPH) in low doses, and prostate cancer in higher doses. It is also indicated for use in combination with doxazosin therapy to reduce the risk for symptomatic progression of BPH.
Finasteride can be used for the treatment of hair loss in men. Finasteride belongs to a class of drugs known as 5-alpha-reductase inhibitors. It works by preventing testosteone from breaking down into DHT, the hormone that is thought to cause male pattern baldness.
Additionally, it is registered in many countries for androgenetic alopecia (male-pattern baldness).
1. Treatment of benign prostatic hyperplasia and treatment of male type hair loss drugs
1) Used for treatment of hair loss;
2) For the treatment of benign prostatic hyperplasia, enlarged prostate shrink, improve urinary flow, and improvement of benign
prostatic hyperplasia caused symptoms.
2. Benign prostatic hyperplasia
Physicians use finasteride for the treatment of BPH, informally known as an enlarged prostate. The FDA-approved dose is
5 mg once a day. Six months or more of treatment with finasteride may be required to determine the therapeutic results
of treatment. If the drug is discontinued, any therapeutic benefits reverse within about -8 months. Finasteride may improve
the symptoms associated with BPH such as difficulty urinating, getting up during the night to urinate, hesitation at the start
of urination, and decreased urinary flow.
3. Male pattern baldness
Finasteride is used to treat male pattern hair loss (androgenetic alopecia) in men only. The treatment provides about 30%
improvement in hair loss after six months of treatment, and effectiveness only persists as long as the drug is taken.
4. Off-label uses
Finasteride is sometimes used in hormone replacement therapy for male-to-female transsexuals in combination with a form
of estrogen due to its antiandrogen properties. However, little clinical research of finasteride use for this purpose has been
conducted and evidence of efficacy is limited.
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