| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Non-Customized |
|
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Praziquantel (Biltricide) is an anthelmintic effective against flatworms. Praziquantel is not licensed for use in humans in the UK; however, it is available as a veterinary anthelmintic, and is available for use in humans on a named-patient basis.
It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system.
Specification of Praziquantel :
|
Items of Test |
Standard |
Result of Test |
|
Descriptions |
White or partially white crystalline powder |
conforms |
|
Melting point |
136-142°C |
137-138°C |
|
Identification |
Consistent with the IR spectrum for reference standard |
Conforms |
|
Loss on drying |
≤0.5% |
0.1% |
|
Residue on ignition |
≤0.1% |
0.02% |
|
Phosphate |
≤0.05% |
<0.05% |
|
Heavy metal |
≤0.002% |
<0.002% |
|
Related substances |
A≤0.2% B≤0.2% C≤0.2% |
0.06% 0.06% ND |
|
Residual solvent |
Ethanol ≤5000ppm Chlorform ≤60ppm |
45ppm ND |
|
Assay |
98.5%-101.0%(dried substance) |
100.5% |
(1) Praziquantel has a particularly dramatic effect on patients with schistosomiasis. Studies of those treated have shown that within six months of receiving a dose of praziquantel, up to 90% of the damage done to internal organs due to schistosomiasis infection can be reversed.
(2) Praziquantel is an anthelmintic or anti-worm medication. It prevents newly hatched insect larvae (worms) from growing or multiplying in your body.
(3) Praziquantel is used to treat infections caused by Schistosoma worms, which enter the body through skin that has come into contact with contaminated water.
(4) Praziquantel is also used to treat infection with liver flukes, caused by a type of worm found in East Asia. This worm enters the body while eating contaminated fish.
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