| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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| Name | Benfotiamine |
| CAS | 22457-89-2 |
| EINECS | 245-013-4 |
| MF | C19H23N4O6PS |
| Grade Standard | Medicine Grade |
| Purity | 98.0%~102.0% |
| Type | Antibiotic and Antimicrobial Agents |
| MW | 466.45 |
| Certificate | ISO |
| Shelf life | 2 Years |
Benfotiamine is vitamin B1 fat soluble derivative, improve the bioavailability of water-soluble vitamin B1 low shortcomings, improve
the blood and tissue concentrations of thiamine, so as to improve the curative effect
Benfotiamine is primarily marketed as an antioxidant dietary supplement. In a clinical study with six patients, benfotiamine lowered AGE by 40%.
Benfotiamine is useful for the treatment of diabetic retinopathy, neuropathy, and nephropathy however "Most of the effects attributed to
benfotiamine are extrapolated from in vitro and animal studies. Unfortunately, apparent evidence from human studies is scarce and
especially endpoint studies are missing. Therefore additional clinical studies are mandatory to explore the therapeutic potential of
benfotiamine in both diabetic and non-diabetic pathological conditions".
It is thought that treatment with benfotiamine leads to increased intracellular thiamine diphosphate levels, a cofactor of transketolase.
This enzyme directs advanced glycation and lipoxidation end products (AGE's, ALE's) substrates to the pentose phosphate pathway,
thus reducing tissue AGEs.
1. Benfotiamine powder is used for the prevention and treatment of vitamin B1 deficiency;
2. For vitamin B1 demand increase, with inadequate intake from foods supplies (fatigue, hyperthyroidism, pregnancy, lactation, during
strenuous manual labor, etc.);
3. Benfotiamine is used in the treatment of nonalcoholic wernicke encephalopathy;
4. To treat beriberi;
5. Used in the following diseases, speculation, and vitamin B1 deficiency and metabolic disorders associated with treatment, such as:
neuralgia; Muscle pain, joint pain; Peripheral neuritis, peripheral nerve palsy; Myocardial metabolic disorders; Constipation and other
gastrointestinal motor function obstacle.
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