| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
|
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1.Quick details of Idebenone Powder
Product Name |
Idebenone Powder,58186-27-9 |
Synonyms |
Idebenone |
CAS No. |
58186-27-9 |
Molecular Formula |
C19H30O5 |
Molecular Weight |
338.44 |
EINECS No. |
1308068-626-2 |
Appearance |
Yellow Crystalline Powder |
Purity |
98%min |
Quality Standard |
Enterprise standard |
Storage conditions |
Store in cool & dry place.Keep away from strong light and heat. |
Packing |
1kg/foil bag;25kg/drum |
Shipment |
EMS;DHL;FedEx;TNT;UPS |
Delivery Time |
4-7 Working Days |
Payment Terms |
T/T;Western Union;MoneyGram;Bitcoin |
2.Production Description of Idebenone Powder
Idebenone is an intelligent promoter; it can activate the function of threaded body, improve the metabolism of brain function
and brain dysfunction, and increase the utilization rate of glucose in brain, promote the generation of ATP; improve the
metabolism of neurotransmitter 5-hydroxytryptamine in brain, and have strong antioxidant and free radical scavenging effects.
In clinic, it is mainly used to treat many degenerative diseases of central nervous system related to oxidative stress, such as
Parkinson's disease, Alzheimer's disease, multi-infarct dementia, local cerebral anemia and brain failure. It is also used to treat
Friedrich's ataxia. It can also be used in cosmetic formulations to eliminate free radicals, inhibit lipid peroxidation, inhibit
inflammation and inhibit DNA. Damage, light protection, reduce pigmentation and other cosmetics efficacy.
Idebenone is also a kind of new drug for treating senile dementia and improving mental symptom.Also, it is a better antioxidant
in cosmetics and health care than Coenzyme Q10 and Vitamin.
3.Specification of Idebenone Powder
|
Test Item |
Analysis Specification |
Result |
|
Description |
An orange yellow or yellow, crystalline powder. |
Conforms |
|
Solubility |
Insoluble in water, freely soluble in anhydrous alcohol. |
Conforms |
|
E1%1cm |
458~486 |
460 |
|
Melting Range: |
52~55°C |
53.2-53.5°C |
|
Loss on drying |
No more than 0.1% |
0.03% |
|
Residue on ignition: |
No more than 0.1% |
0.03% |
|
Heavy metals |
No more than 10ppm |
Conforms |
|
Impurities(HPLC) |
No more than 0.8% |
0.6% |
|
Assay(HPLC) |
No less than 98.5% (on the dried Basis) |
99.6% |
|
Conclusion |
Conform to Enterprise Standard |
|
Don't hesitate to contact us for latest COA and Test Report of Idebenone Powder
Idebenone is used for depressive disorders (endogenous and non-endogenous depression), severe patients have significant
or persistent depression or restlessness (lasting for at least 2 weeks), mainly including the following symptoms:depression, loss
of interest, significant changes in weight or appetite, insomnia or lethargy, psychomotor excitement or retardation,excessive fatigue,
guilt or inferiority, slow thinking or inattention. Suicide attempts or ideas. It is also used for depression associated with physical
diseases, such as post-stroke depression. It can also be used as an adjuvant for the treatment of anxiety disorder,panic disorder
and chronic pain.
1. Idebenone increases nerve factor (NGF) in the brain.
2. Idebenone is a powerful antioxidant and positively affects brain chemistry.
3. Idebenone has been shown to promote information transfer across the corpus callosum, the membrane separating the
right and left brain hemispheres.
4. Idebenone has been used to treat Alzheimer's and to lessen damage from strokes.
5. Idebenone can increase production of the brain neurotransmitters serotonin, dopamine, adrenalin, and noradrenanlin.
6.Work of Idebenone Powder
Idebenone absorbs electrons from free radicals called reactive oxidative species (ROS) in the mitochondria, preventing oxidative
damage in cells. This improves the survival and recovery of cells. Additionally, by moving electrons down the electron transport
chain, idebenone can restore energy (ATP) production in damaged cells.
Although glutamate is an important neurotransmitter, excess levels can cause issues in the brain. Idebenone can prevent brain
cell death (neuronal death) due to oxidative stress that is sometimes caused by glutamate. Idebenone also increases nerve
factor (NGF) levels, a neurotransmitter responsible, development, and survival of neurons. Increased
nerve levels can improve overall cognitive function.
7.Side Effect of Idebenone Powder
The incidence of side effects was 3.77% (45/1193).
Allergies: occasional rashes, etc., should be discontinued.
(2) Digestive system: occasional nausea, loss of appetite, stomachache, diarrhea, etc.
(3) Nervous system: occasional hyperactivity, spasmodic seizures, rare vertigo, hobble, excitement, etc.
Blood: occasional erythrocytopenia, leukopenia, etc.
Liver: Incidental elevation of SGOT, SGPT and ALP.
Kidney: Incidental BUN elevation.
Others: Incidental increases in burnout, total cholesterol and triglycerides.
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