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Product Name
|
Oleoylethanolamide(OEA) |
CAS
|
111-58-0 |
EINECS NO.
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203-884-8 |
Molecular formula
|
C20H39NO2 |
Molecular weight
|
325.529 |
Boiling point
|
496.4±38.0 °C at 760 mmHg |
Oleoylethanolamine (OEA) is an endogenous peroxisome proliferator-activated receptor alpha (PPAR-α) agonist. It is a naturally occurring ethanolamide lipid that regulates feeding and body weight in vertebrates ranging from mice to pythons.
OEA is a shorter, monounsaturated analogue, but unlike anandamide it acts independently of the, regulating PPAR-α activity to stimulate lipolysisOleoylethanolamide (OEA) is a natural metabolite that is made in small amounts in your small intestine. OEA helps regulate hunger, weight, body fat and cholesterol by binding to a receptor known as PPAR-Alpha (Peroxisome proliferator-activated receptor alpha). In essence, OEA increases the metabolism of body fat and tells your brain that you are full and it's time to stop eating. OEA is also known to increase non-exercise related calorie expenditure.
Oleoylethanolamide (OEA) works to activate something called PPAR and simultaneously ramps up fat-burning and decreases fat storage. When you eat, OEA levels increase and your appetite decreases when the sensory nerves that link to your brain tell it that you're full. PPAR-α is a group of ligand-activated nuclear receptor that involved in the gene expression of lipid metabolism and energyhomeostasis pathways.