| Powder: | Yes |
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| Customized: | Non-Customized |
| Certification: | GMP, HSE, ISO 9001, USP, BP |
| Suitable for: | Adult |
| State: | Solid |
| Purity: | >99% |
| Samples: |
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| Customization: |
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English Name: Fluoxetine hydrochloride
English synonym: -methyl-gamma- (+) (4- (trifluoromethyl) phenoxy) 3- (p-trifluoromethylphenoxy) benzenepropanaminehydrochlorid; -n-methyl-3-phenylpropylaminehydrochloride; fontex; lilly110140; n-methyl-3-phenyl-3- (p-trifluoromethylphenoxy) -propylaminhydrochloride; FLUOXETINE-D5 HCL; FLUOXETINE-D5 HCL; FLUOXETINE-D5 HYDROCHLORIDE (PHENYL-D5)
CAS: 56296-78-7
Molecular formula: C17H19ClF3NO
Molecular weight: 345.79
EINECS: 260-101-2
Related categories: Intermediates & Fine Chemicals; Isotope Labeled Compounds; Pharmaceuticals; Serotonin; Amines; Aromatics; Isotope Labelled Compounds; raw material; pharmaceutical intermediates; pharmaceutical raw materials; small molecule inhibitors; medicine
Mol file: 56296-78-7.mol
Fluoxetine hydrochloride is a selective serotonin reuptake inhibitor (SSRI),it is adapted to the treatment of various depressive disorders, including mild or major depression, bipolar disorder depression, psychogenic depression and depressive neurosis. The mechanism is inhibiting neuronal uptake of serotonin from the synaptic cleft, increasing this neurotransmitter in the gap for practical use , thereby improving the emotional state,and treating depressive disorders. Common adverse reactions are dry mouth, loss of appetite, nausea, insomnia, fatigue, a few cases of anxiety and headaches are seen .
Because fluoxetine hydrochloride has longer half-life, patients whose liver and kidney function are poor or elderly patients, should appropriately reduce the dose. Children should be applied in accordance with the doctor's advice. Patients who has the history of epilepsy, pregnancy or lactation women should use with caution . If rash or fever occurs, the drug should be discontinued immediately and symptomatic treatment should be given. It is not appropriate to be used with monoamine oxidase inhibitor (MAOI) ; if necessary, the drug should be discontinued after five weeks, before switching to a monoamine oxidase inhibitor (MAOI).
Fluoxetine 20mg blister pack
Fluoxetine is frequently used to treat major depressive disorder, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), bulimia nervosa, panic disorder, premenstrual dysphoric disorder, and trichotillomania.It has also been used for cataplexy, obesity, and alcohol dependence,as well as binge eating disorder.It has also been tried as a treatment for autism spectrum disorders with moderate success in adults.
Obsessive-compulsive disorder:
The efficacy of fluoxetine in the treatment of obsessive-compulsive disorder (OCD) was demonstrated in two randomized multicenter phase III clinical trials. The pooled results of these trials demonstrated that 47% of completers treated with the highest dose were "much improved" or "very much improved" after 13 weeks of treatment, compared to 11% in the placebo arm of the trial.The American Academy of Child and Adolescent Psychiatry state that SSRIs, including fluoxetine, should be used as first-line therapy in children, along with cognitive behavioral therapy (CBT), for the treatment of moderate to severe OCD.
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