Local Anesthetic Powder 99% Dyclonine Hydrochloride 536-43-6

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Adult
• State: Solid
• Purity: >98%
• Model NO.: TGY072019041607
• Product Name: Dyclonine Hydrochloride
• Appearance: White Powder
• Test Methods: HPLC
• Shelf Life: 2 Years
• Shipping Methods: DHL, FedEx, TNT and EMS
• MOQ: 10g
• CAS No.: 536-43-6
• Sample: Available
• Transport Package: Foil Bag, Box, Drum
• Specification: 98% min
• Trademark: TGY
• Origin: China
• HS Code: 3101001100
• Production Capacity: 100kg/Month

Product Description

_{English name: dyclonine
English alias: Dyclocainum; 1 - (4 - butoxyphenyl) - 3 - - ylpropan piperidin - 1-1 - one; 4 '- Butoxy - 3 - N - piperidino - propiophenon Dyclon; Diclonina [INN - Spanish]; 1 - (4 - butoxy - phenyl) - 3 - piperidin - 1 - yl - propan - 1 - one
CAS no. : 586-60-7
Formula: C18H27NO2
Molecular weight: 289.41200
Density: 1.017 g/cm3
The boiling point: 424.5 is now C at 760 mmHg
Flash: DHS 210.5 C
Refractive index: 1.517
Application: 
This product can prevent all kinds of transmission of nerve impulses or stimulate, inhibit the sense of touch and pain, is pain, itching and antiseptic effect to the skin.}

<sub>Dyclonine Hydrochloride is the hydrochloride salt of Dyclonine, an unclassified compound with local anesthetic effect. Dyclonine reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal membrane's permeability to sodium ions, leading to an increased threshold for excitation. This reversibly stabilizes the membrane and inhibits depolarization, leading to the failure of a propagated action potential and subsequent conduction blockade. This results in a transient and reversible loss of sensation in a localized area of the body.


1.The ideal topical anesthetic agent should have the following properties: rapid onset of effect; high potency, low sensitizing potentiality;no irritation; safety, even if absorbed; no cross sensitivity with other local anesthetic agents</sub>

 

Name	Dyclonine HCl	Batch No.	071003
Date Of Produce	20071020	Date Test	20071021
Exp Date	2010/10/19	Inspection basis	USP 28
Test Items	Specification		Test Results
Appearance	A white or almost white crystalline		A white powder
Identification	A,B,C in Pass		Complies
Melting Point	173 - 178ºC		173.5 -175.5ºC
Acidity	4.0 - 7.0		5.8
Loss on drying	≤1.0 %		0.47 %
Residue on ignition	≤0.2 %		0.06 %
Assay	98 - 102 %		99.93 %
Conclusion	Pass USP 28

 

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