Customization: | Available |
---|---|
Powder: | Yes |
Customized: | Customized |
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Dyclonine Hydrochloride is the hydrochloride salt of Dyclonine, an unclassified compound with local anesthetic effect. Dyclonine reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal membrane's permeability to sodium ions, leading to an increased threshold for excitation. This reversibly stabilizes the membrane and inhibits depolarization, leading to the failure of a propagated action potential and subsequent conduction blockade. This results in a transient and reversible loss of sensation in a localized area of the body.
1.The ideal topical anesthetic agent should have the following properties: rapid onset of effect; high potency, low sensitizing potentiality;no irritation; safety, even if absorbed; no cross sensitivity with other local anesthetic agents
Name | Dyclonine HCl |
Batch No. |
071003 |
Date Of Produce |
20071020 | Date Test |
20071021 |
Exp Date |
2010/10/19 | Inspection basis |
USP 28 |
Test Items |
Specification |
Test Results |
|
Appearance |
A white or almost white crystalline | A white powder | |
Identification |
A,B,C in Pass | Complies | |
Melting Point |
173 - 178ºC | 173.5 -175.5ºC | |
Acidity |
4.0 - 7.0 | 5.8 | |
Loss on drying |
≤1.0 % | 0.47 % | |
Residue on ignition |
≤0.2 % | 0.06 % | |
Assay |
98 - 102 % | 99.93 % | |
Conclusion |
Pass USP 28 |