| Customization: | Available |
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| Certification: | RoHS, ISO, FDA, HACCP |
| Assay Method: | HPLC, UV |
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Hirudin is one of the most active components extracted from leech and its salivary gland. It is a small protein (polypeptide) composed of 65-66 amino acids. Leeches are rich in hirudin. Hirudin has a strong inhibitory effect on thrombin, which is the strongest natural specific inhibitor of thrombin. Hirudin has a strong effect of inhibiting blood coagulation and antithrombotic,
and has a broad application prospect in clinical treatment and prevention of various thrombosis.
1.Animal studies and clinical studies have shown that hirudin is highly effective in anticoagulant, antithrombotic, and blocking of thrombin-catalyzed activation of blood coagulation factors and platelet response and other bloody phenomena.
2.In addition, it also inhibits thrombin-induced proliferation of fibroblasts and thrombin stimulation of endothelial cells. Compared with heparin, it not only uses less, does not cause hemorrhage, and does not depend on endogenous cofactors; heparin has the risk of causing hemorrhage and antithrombin III during the course of diffuse intravascular coagulation. It is often reduced, which will limit the efficacy of heparin, and the use of blisters will have a better effect.
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