| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
|
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Product Name |
Tideglusib |
Other Name |
4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione |
|
CAS No. |
865854-05-3 |
Appearance |
White powder |
|
MF |
C19H14N2O2S |
MW |
334.39 |
|
Specification |
99% |
Testing Method |
HPLC |
Tideglusib (NP-12, NP031112) is a potent, selective and irreversible small molecule non-ATP-competitive glycogen synthase kinase 3 (GSK-3) inhibitor.. Other GSK inhibitors. There are few classes of GSK-inhibitors, including lithium (Martinez et al., 2011), the small peptide L803mts10, and members of the thiazolidinedione family, containing non-competitive inhibitors of GSK-3, such as TDZD-8.Tideglusib is a GSK-3 inhibitor currently in phase II clinical trials for the treatment of Alzheimer disease and progressive supranuclear palsy.
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