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Product Name | Paroxetine |
MF | C19H20FNO3 |
MW | 329.37 |
CAS | 61869-08-7 |
PAROMOMYCINSULFATE;(3s,4r)-orid;(3s-trans)-id;3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)-,hydrochloride,(3s-trans)-piperidin;3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)-piperidinhydrochl;PAROXETINE HC;Paroxetine hydrochloride,trans-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine hydrochloride;(3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-piperidine hydrochloride hemihydrate
paroxetine hydrochloride (paroxetine, paxil), the scientific name of floperidol, is a phenyl piperidine compound, developed by GlaxoSmithKline company, launched in 1991. It has a highly selective -HT reuptake blocking effect, and its antidepressant intensity is similar to tricyclic antidepressants (TCAs), but the side effects are significantly smaller than tricyclic antidepressants (TCAs), which belongs to the third generation of antidepressant drugs.
Paroxetine, (-) -trans-4 -(4-fluorophenyl)-3-[[3,4-(methodioxy) phenoxy] methyl] -piperidine, which is a selective 5-HT reuptake inhibitor, has no significant effect on other transmitters when commonly administered. Increases the concentration of -HT in the synaptic gap by preventing the reabsorption of 5-HT, resulting in an antidepressant effect. Paroxetine works by inhibiting 5-TH reuptake of brain neurogen and is more selective than fluoxetine, sertraline or clomipramine. The affinity to cholinergic, histamine or adrenoergic receptors is low, and the anticholinic and cardiovascular adverse reactions are less than tricyclic antidepressants.