| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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Product Name |
Citalopram Hydrobromide,59729-32-7 |
Synonyms |
Citalopram hydrobromide, 95%, selective serotonin reuptake inhibitor (SSRI) |
CAS No. |
59729-32-7 |
Molecular Formula |
C20H22BrFN2O |
Molecular Weight |
405.3 |
EINECS No. |
261-890-6 |
Appearance |
White to off-white crystalline powder |
Purity |
98%min |
Quality Standard |
Enterprise standard |
Storage conditions |
Store in a cool & dry place. Keep away from strong light and heat. |
Packing |
1kg/foil bag;25kg/drum |
Shipment |
EMS;DHL;FedEx;TNT;UPS |
Delivery Time |
4-7 Working Days |
Payment Terms |
T/T; Western Union; MoneyGram; Bitcoin |
Citalopram Hydrobromide is an antidepressant drug of the selective serotonin reuptake inhibitor (SSRI) class. It has the U.S.
Food and Drug Administration approval to treat major depression, which it received in 1998, and is prescribed off-label for
other conditions. In Australia, the UK, Germany, Portugal, Poland, and most European countries, it is licensed for depressive
episodes and panic disorder with or without agoraphobia. In Spain, it is also used for obsessive-compulsive disorder.
ITEMS |
SPECIFICATION | TEST RESULTS |
Appearance |
Off-white or white powder | Conforms |
Identification |
HPLC, NMR; LC-MS | Conforms |
Related substances |
Individual impurity≤0.5% | 0.09% |
| Total impurities≤1.0% | 0.20% | |
Loss on drying |
≤0.5% | 0.3% |
Residue on ignition |
≤0.1% | 0.04% |
Heavy metals |
≤10ppm | Conforms |
Assay |
≥98.0 % | 99.1% |
Citalopram Hydrobromide is used for depressive disorders (endogenous and non-endogenous depression), severe patients
have significant or persistent depression or restlessness (lasting for at least 2 weeks), mainly including the following symptoms:
depression, loss of interest, significant changes in weight or appetite, insomnia or lethargy, psychomotor excitement or retardation,
excessive fatigue, guilt or inferiority, slow thinking or inattention. Suicide attempts or ideas. It is also used for depression associated with physical diseases, such as post-stroke depression. It can also be used as an adjuvant for the treatment of anxiety disorder, panic disorder, and chronic pain.
Dosage of Citalopram Hydrobromide Powder
Oral: Adults once a day. The initial dose is 20 mg per day, which can be increased to 40-60 mg per day if a clinical need arises.
The dosage of patients over 65 years old was reduced by half (10-30 mg per day). Antidepressant treatment must last for an
appropriate period of time. It takes 4 to 6 months for the manic-depressive disorder. If insomnia or severe inability to sit still occurs,
sedatives should be supplemented in the acute phase. Children's clinical experience is unknown, please follow the doctor's advice.
Drug Interaction of Citalopram Hydrobromide Powder
The Patients who taking monoamine oxidase inhibitors should not use citalopram hydrobromide at the same time. Citalopram
hydrobromide can be used after 14 days of discontinuation of the monoamine oxidase inhibitor. However, if a reversible
monoamine oxidase inhibitor with a short half-life, such as moclobemide, is used, citalopram hydrobromide can be used after
one day of withdrawal.
Side Effect of Citalopram Hydrobromide Powder
Citalopram Hydrobromide's Side effects are usually rare, mild, and transient. The most common adverse reactions were nausea,
increased sweating, reduced salivation, headache, and shortened sleep time. It is usually evident in the first or second week of
treatment and generally disappears as depression improves. Epilepsy seizures have been observed in rare cases. In patients
with bradycardia, bradycardia can make treatment more complex.
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