API 98% Macitentan Powder CAS 441798-33-0

• Powder: Yes
• Customized: Customized
• Certification: ISO 9001
• Suitable for: Adult
• State: Solid
• Purity: >98%
• Model NO.: 201904180311
• Name: Macitentan
• Other Names: Macitentan Powder
• Other Name: Macitentan Capsules
• CAS: 441798-33-0
• Einecs: 1308068-626-2
• Molecular Formula: C19h22br2n6o4s
• Molecular Weight: 590.295
• Content: 98%
• Color: White
• Form: Powder
• Function: Health Care
• Grade: Medcine
• MOQ: 5g
• Storage: Cool Dry Place
• Shelf Life: 2 Years
• Transport Package: Foil Bag
• Specification: 98%
• Trademark: TGYBIO
• Origin: China
• HS Code: 000
• Production Capacity: 20kg/Month

Product Description

Macitentan is a non-chiral sulphadiazine derivative. In vitro studies have shown that it is an oral active antagonist of endothelin ETA and ETB receptor, which can block endothelin-induced vasoconstriction in trachea and aorta. Developed by Swiss company Actelion Pharmaceuticals and first marketed in the United States with FDA approval on October 18, 2013, it is mainly used to treat pulmonary hypertension (PAH) and its product name is Opsumit. Compared with other drugs for pahs, masititan can significantly reduce the morbidity and mortality of pahs patients mainly by slowing the progression of disease.