| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
|
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| Brand | TGY |
| Product Name |
Orlistat |
| CAS No. |
96829-58-2 |
| EINECS |
639-755-1 |
| Molecular Formula |
C29H53NO5 |
| Molecular Weight |
495.73 |
| Appearance | White Powder |
| Purity |
99% |
Orlistat is used for the treatment of obesity. The amount of weight loss achieved with orlistat varies. In one-year clinical trials, between 35.5% and 54.8% of subjects achieved a 5% or greater decrease in body mass, although not all of this mass was necessarily fat.
Between 16.4% and 24.8% achieved at least a 10% decrease in body mass. After orlistat was stopped, a significant number of
subjects regained weight up to 35% of the weight they had lost. The incidence of type 2 diabetes in an obese population over
four years is decreased with orlistat (6.2%) compared to placebo (9.0%). Long-term use of orlistat also leads to a modest
reduction in blood pressure (mean reductions of 2.5 and 1.9 mmHg in systolic and diastolic blood pressure respectively).
COA of Orlistat
|
Item |
Requirements |
Test Results |
|
Appearance |
while to off-white powder |
White powder |
|
Identification |
HPLC retention time |
Conforms |
|
Melting Point |
42 ºC -45°C |
42°C-44°C |
|
Specific optical rotation |
-31.0°~-41.0° |
-36.0° |
|
Purity by HPLC |
no less than 98.0% |
98.5% |
|
Total impurity |
no more than 2.0% |
1.6% |
|
Max Individual impurity |
no more than 0.5% |
0.3% |
|
Water content%(K&F) |
no more than 0.5% |
0.1% |
|
Residual solvents |
EtOH no more than 0.5% |
N.D |
|
EtAC no more than 0.5% |
N.D |
|
|
Residue on ignition |
less than 0.2% |
0.10% |
|
Heavy metals as Pb |
no more than 20ppm |
less than20ppm |
|
Assay (HPLC) |
no less than 98.0% |
98.60% |
|
Conclusion |
Meets the Requirements |
|
Orlistat is used with a low-calorie diet to help you lose weight and maintain your weight after weight loss.
Orlistat is in a class of drugs called lipase inhibitors. It works in your intestines, where it blocks some of the fat you eat from being
absorbed and digested. This undigested fat is then removed from your bowel movements.
1. As pharmaceutical raw materials
2. Health care products
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