99% High Purity Anti Tumor Lenalidomide CAS 191732-72-6

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Adult
• State: Solid
• Purity: >99%
• Model NO.: TGY022019042804
• Product Name: Lenalidomide
• Appearance: White Powder
• Specificcation: 99%
• CAS No.: 191732-72-6
• Grade: Pharmaceuticals Grade
• Shelf Life: 2 Years
• Storage: Cool Dry Place
• Shipping Time: Within 3-7 Working Days
• Transport Package: Foil Bag, Box, Drum
• Specification: 99% min
• Trademark: TGY
• Origin: China
• HS Code: 3001200010
• Production Capacity: 1500kg/Month

Product Description

 _{99% High Purity Anti Tumor Lenalidomide CAS 191732-72-6
CAS number: 191732-72-6
Pharmacopoeia: Chinese Pharmacopoeia
CAS number: 191732-72-6
Molecular formula: C13H13N3O3
English Name: Lenalidomide
English synonyms: 3 - (7-amino-3-oxo-1h-isoindol-2-yl) piperidine-2,6-dione; LenalidomideLenalidomide; 1-Oxo-2- 2,6-dioxopiperidin-3-yl -4-aminoisoindoline; 3 - (4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl) -2,6-piperidinedione; CC-5013; Revlimi; lenalidomide (other anti-cancers); 3 4-amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl piperidine-2,6-dione
Molecular weight: 259.2606
Melting point: 269-271
Boiling point: 614 at C 760 mmHg
Density: at 5.2E-15mmHg 25 C
Flash point: 325.1 ~ C
Anti tumor}
 

<sub>At present, there are many main aspects about the anti-cancer effect of the lenalidomide. Respectively, they are: inhibiting the formation of tumor nourishing blood vessels, stimulating the activation of T lymphocytes, the direct anti-tumor effect. Existing studies have shown that the monocytes in human bodies can be produced in inflammatory environment (local tissues can be caused to keep in inflammatory environment in each stage when the tumor is producing).

As for the immunomodulatory drugs such as lenalidomide, one of the important function is that it can inhibit monocytes to produce TNF-α. When TNF-α is reduced, it will be very difficult for the tumor to produce new blood vessels. Moreover, with less blood vessels producing, not only the tumor will be "starved" because of "malnutrition", but also the tumor cells will be very hard to transfer to other human parts through blood. So, it may be said "kill two birds with one stone". Except the action target TNF-α, lenalidomide can also reduce one kind of active substance named COX-2 which can stimulate blood vessels around the tumor to produce. There are many COX-2 in some tumor cells. In addition, with the deepening of the research, the researchers also found that lenalidomide can inhibit IL - 6 which can stimulate blood vessels around the tumor to produce.

As for the immunomodulatory drugs such as lenalidomide, one of the important function is that it can inhibit monocytes to produce TNF-α. When TNF-α is reduced, it will be very difficult for the tumor to produce new blood vessels. Moreover, with less blood vessels producing, not only the tumor will be "starved" because of "malnutrition", but also the tumor cells will be very hard to transfer to other human parts through blood. So, it may be said "kill two birds with one stone". Except the action target TNF-α, lenalidomide can also reduce one kind of active substance named COX-2 which can stimulate blood vessels around the tumor to produce. There are many COX-2 in some tumor cells. In addition, with the deepening of the research, the researchers also found that lenalidomide can inhibit  IL - 6 which can stimulate blood vessels around the tumor to produce.</sub> 

Test Items	Specification	Results
Description	White to off white crystalline powder	Comply
Melting point	166-170°C	167.3-168.1°C
Identification	Positive reaction	Positive reaction
Related substances	≤1.0%	0.16%
Loss on drying	≤0.5%	0.06%
Residue on ignition	≤0.1%	0.02%
Chloride	≤0.014%	<0.014
Heavy Metals	≤20ppm	<20ppm
Clarity of solution	Conform to standard	Complies
Microbial Limit	≤20ppm	<20ppm
Assay	≥99.0%	99.12%

 

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