| Powder: | Yes |
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| Customized: | Customized |
| Certification: | GMP, ISO 9001, USP, BP |
| Suitable for: | Elderly, Adult |
| State: | Powder/Capsule |
| Purity: | >98% |
| Samples: |
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| Customization: |
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99% Vitamin B3 Capsule Nicotinamide Powder CAS 98-92-0 Skin Whiten Nicotinamide
Nicotinamide Basic information |
|
| Product Name: | Nicotinamide |
| Synonyms: |
3-PYRIDINECARBOXAMIDE;3-PYRIDINE CARBOXYLIC ACID AMIDE;3- PYRIDINECARBOXYLIC AMIDE;TIMTEC-BB SBB004283;NICETHAMIDUM: NIACINAMIDE;NICOTINIC ACID AMIDE;NICOTINAMIDE |
| CAS: | 98-92-0 |
| MF: | C6H6N2O |
| MW: | 122.12 |
| EINECS: | 202-713-4 |
| Product Categories: |
Pharmaceutical intermediates;Miscellaneous Compounds;Aromatics; Nicotine Derivatives;Inhibitors;Biochemistry;Vitamins;Nutritional Suppleme nts;Vitamins and derivatives;Vitamin Ingredients;Vitamin series;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;vitamin; Other APIs;Cosmetics;food additive;Cosmeitc raw materials |
| Mol File: | 98-92-0.mol |
Nicotinamide is a watersoluble vitamin, The product is white crystalline powder, odorless or nearly odorless, bitter in taste, freely soluble in water or ethanol, dissolvable in glycerin.
Nicotinamide is easy to absorb oral, and can be widely distributed in the body, the excess metabolites or prototype quickly expel from urine. Nicotinamide is part of coenzyme I and coenzyme II, plays the role of hydrogen delivery in biological oxidation respiratory chain, can promote biological oxidation processes and tissue metabolism, maintain normal tissue (especially the skin, digestive tract and nervous system) integrity has an important role.
In addition, nicotinamide has prevention and treatment of heart block, sinus node function and anti-fast experimental arrhythmias, nicotinamide can significantly improve the heart rate and atrioventricular block caused by verapamil.
Specification:
Nicotinamide Chemical Properties |
|
| Melting point | 128-131 °C(lit.) |
| Boiling point | 150-160 °C |
| density | 1.4 |
| refractive index | 1.4660 (estimate) |
| Fp | 182 °C |
| storage temp. | 0-6°C |
| solubility | 691g/l |
| pka | 3.3(at 20ºC) |
| form | powder |
| color | white |
| PH | 6.0-7.5 (50g/l, H2O, 20ºC) |
| Water Solubility | 1000 g/L (20 ºC) |
| Merck | 146,523 |
| BRN | 383619 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| InChIKey | DFPAKSUCGFBDDF-UHFFFAOYSA-N |
| CAS DataBase Reference | 98-92-0(CAS DataBase Reference) |
| NIST Chemistry Reference | Niacinamide(98-92-0) |
| EPA Substance Registry System | 3-Pyridinecarboxamide(98-92-0) |
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Nicotinamide is a structural form of B vitamins and is an important component of coenzyme I and coenzyme II in humans and animals.
It is mainly used in the fields of medicine, food and feed additives.
1.Feed additive
Nicotinamide is the main efficacy and use of feed additives:
1) Prevent skin lesions and digestive tract diseases.
2) Promote the growth of livestock and poultry, increase the egg production and hatching rate, and ensure the feathers are well developed.
3) Treat mucosal inflammation and ulcers.
4) Prevent short bone disease in livestock and poultry.
If the livestock lacks nicotinamide, it will cause: skin changes in the birds, feather reduction and dermatitis; pigs will have hair loss and
dermatitis. Inflammation of the mouth, tongue and esophagus, such as black tongue. Digestive disorders, such as vomiting, diarrhea,
and reduced food intake. Nervous system disorders, muscle spasms and paralysis. Posterior ankle joint hypertrophy (especially poultry)
and short bones.
2. Medicines and food additives
The main functions and uses of nicotinamide in medicines and food additives:
1) Prevention and treatment of skin lesions and digestive tract diseases such as: pellagra, dermatitis, black tongue disease, vomiting, diarrhea, etc.
2) Promote the metabolism of substances and energy in the body and promote the normal growth and development of the human body.
3) Used in combination with other drugs to treat various mucosal inflammations and ulcers.
4) Strong vasodilating effect, improve blood supply function in the body, and have certain curative effect on cerebral thrombosis, coronary
heart disease and hyperlipidemia.
5) Supplements niacin and nicotinamide deficiency caused by long-term use of isonicotinic acid and its analogues.
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